Developing treatment for
eye infection

News

2011-08-22

New drug for epidemic keratoconjunctivitis EKC

Pressrelease August 22, 2011
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Adenovir Pharma

Adenovir Pharma AB is a development company developing new solutions for treatment of infectious diseases affecting the eyes.

 

Adenovir Pharma was founded by researchers at the department of Virology, Umeå University, Sweden and P.U.L.S. AB which acts as an incubator and financer for early stage projects within life science. Adenovir Pharma is located in Helsingborg Sweden in one of Europe’s premier biotechnology regions, Medicon Valley. The initial development has been conducted at the University of Lund, Department of Organic Chemistry and at the University of Umeå, Department of Virology and in collaboration with P.U.L.S. AB and external service providers.

 

With unique patented technology and own product concepts, Adenovir Pharma aim to offer new treatments and business development opportunities to the pharmaceutical industry. The goal is to develop a new antiviral medicinal product for the treatment and prevention of epidemic keratoconjunctivities (EKC).

Disease Focus/Customer Focus

Epidemic keratoconjunctivitis, EKC, is a serious viral  eye infection.  EKC is a highly contagious disease that can be found all over the world, but is more common in heavily populated countries in Asia. Adenovirus conjunctivitis is particularly problematic in Japan where there are about one million cases of EKC each year. EKC is a disease where there is a lack of effective treatment and it represents a large unmet medical need.

 

Mission/Strategies

 

The aim is to develop a new antiviral medicinal product for the treatment of EKC. The strategy is to develop the product up to Ph I and a Ph IIa and clinical Proof-of-Concept and continue further development up to approval with a partner.

 

Technology Platform

 

The aim is develop a topical pharmaceutical product preventing certain adenoviruses from binding to the receptors in the human eye. By using Adenovir Pharma’s unique proprietary technology, the viruses are aggregated and inhibited from binding to and infecting human corneal cells. The product acts outside the human cells, and there is low risk for development of viral resistance. 

 

Development to date

 

Adenovir Pharma has developed a new carrier which has been in vitro tested, early toxicity studies, filed a new patent application, completed formulation, manufactured a documented tech batch, conducted a preclinical toxicology program, GMP-production and is now planning to conduct a clinical trial program in 2012.

 

Outlook

 

CTA filing for Ph I studies